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| | Skin Pigment Disorders |
What are skin pigment disorders?
Skin color is determined by a pigment (melanin) made by specialized cells in the skin (melanocytes). The amount and type of melanin determines a person's skin color.
What is the function of melanin?
Melanin gives color to the skin, hair, and iris of the eyes. Levels of melanin depend on race and amount of sunlight exposure. Sun exposure increases melanin production - to protect the skin against harmful ultraviolet rays. In addition, hormonal changes can affect melanin production.
What are the different types of skin pigment disorders?
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Pigment Disorder
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Characteristics
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Treatment
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albinism
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This rare, inherited disorder is characterized by a total or partial lack of melanin in the skin, compared to the pigmentation of siblings and parents. Albinos (people with albinism) have white hair, pale skin, and pink eyes. Vision is often affected.
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There is no cure for albinism. Albinos should avoid sunlight because they lack natural protection from sunlight - melanin.
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pigment loss after skin damage
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Sometimes following an ulcer, blister, burn, or infection, the skin does not replace some of the pigment in that area.
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No treatment is necessary. Cosmetics can usually cover the blemish.
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vitiligo
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Smooth, white patches in the skin. Vitiligo is caused by the loss of pigment-producing cells in the skin (melanocytes). The white patches are very sensitive to the sun.
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There is no cure for vitiligo. Treatment may include covering smaller patches with long-lasting dyes, light-sensitive drugs, in addition to ultraviolet A light therapy, corticosteroid creams, and depigmentation of the remaining skin.
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Lucile Packard Children's Hospital is located in Palo Alto, adjacent to Stanford University Hospital, approximately 20 miles north of San Jose, CA and 40 miles south of San Francisco.
Lucile Packard Children's Hospital
725 Welch Road
Palo Alto, California 94304
(650) 497-8000
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