X-linked Dominant: Incontinentia Pigmenti
What is X-linked dominant inheritance?X-linked dominant inheritance occurs when the gene is located on the X chromosome, but the gene acts in a dominant manner. This means that both males and females can display the trait or disorder, when they only have one copy of the gene.
What is incontinentia pigmenti (IP)?IP is extremely rare. The main features occur in the skin where a blistering rash occurs in the newborn period, followed by the blisters becoming raised-like warts. Next, brown swirls appear in the skin, followed by the appearance of light swirls. The result is a "marble cake-like" appearance on the skin. Other health problems can be seen in IP involving the eyes, central nervous system, teeth, nails, and hair. The severity varies from person to person.
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